The innervation of different joint elements, including the periosteum, subchondral bone, ligaments, menisci and synovium, is modulated via the regional release of sensory neuropeptides from afferent neurons, resulting in the phenomenon of neurogenic inflammation that exacerbates the release of inflammatory mediators from cellular harm. Warning: Undefined array important "background_im... https://beaudtrai.aioblogs.com/89858459/the-non-pharmaceutical-pain-relief-diaries