Activation of neuronal CB1 receptors ends in inhibition of adenylyl cyclase and diminished neurotransmitter release through blockade of voltage-operated calcium channels.[46,65,125] The activation of these signaling pathways by CB1 receptors along with the large amounts of these receptors on presynaptic terminals indicates that endocannabinoid stimulation of CB1 receptors suppresses n... https://cashtldua.spintheblog.com/33105943/little-known-facts-about-tetrahydrocannabinol